Arup and global contracting and investment firm Rönesans Holding are pleased to announce that Istanbul’s Başakşehir Pine and Sakura City Hospital, the largest base-isolated building in the world, has officially opened after partially opening last month to help with the ongoing COVID-19 pandemic. Along with Perkins & Will and Yazgan Design Architecture, Arup collaborated with Rönesans Holding and Sojitz Corporation, a Japanese investment and trade corporation, to design and bring to life the hospital, which spans one million m2 of construction area and features 2,068 seismic isolators. As the structural engineer for the project, Arup ensured the seismic resilience of the large-scale hospital, which is located near the North Anatolian fault in an area that has suffered highly destructive earthquakes in the past.